Chicken Soup for the Soul by Jack Canfield and Mark Victor Hansen
Within a month of submitting the first manuscript to publishing houses, the creative team behind this multimillion dollar series got turned down 33 consecutive times. Publishers claimed that "anthologies don't sell" and the book was "too positive." Total number of rejections? 140. Then, in 1993, the president of Health Communications took a chance on the collection of poems, stories, and tidbits of encouragement. Today, the 65-title series has sold more than 80 million copies in 37 languages.