This epic science-fiction story was rejected by 23 publishers before being accepted by Chilton, a small Philadelphia publisher. Dune quickly became a success, winning awards such as the Hugo Award for Best Novel in 1966. Dune was followed by five sequels, and though none did as well as the original, a film version of the book starring rock star Sting did quite well and remains a cult favorite.
Helen Davies, Marjorie Dorfman, Mary Fons, Deborah Hawkins, Martin Hintz, Linnea Lundgren, David Priess, Julia Clark Robinson, Paul Seaburn, Heidi Stevens, and Steve Theunissen
HowStuffWorks looks at the surprising relationship between syphilis and smallpox.