This fiery, petite Italian-American was born in 1958 in Bay City, Michigan. From the start, Madonna Louise Veronica Ciccone had big dreams, and at 19 she moved to New York City where she began to make a name for herself as a singer and dancer.
Selling more than 200 million albums in a career that has spanned more than two decades, "Madge" has stayed on top by constantly reinventing herself. Though many disagree with some of her artistic choices, the numbers don't lie: Billboard magazine reports that Madonna's 2006 Confessions tour was the most successful concert tour by a female artist in history.
Here are 25 of the biggest hits that put her on top.