Madonna's Most Popular Songs, 21-25

Here is our final set of Madonna's 25 most popular songs, starting with "American Pie."

21. "American Pie" (2000)

Don McLean's classic tune got the Madonna treatment for inclusion in the movie The Next Best Thing. The movie flopped, but the song did well -- reaching number one in the U.K., Canada, and Australia, among others. Oddly enough, although the song wasn't released in the States, it reached number 29 off airplay alone.

22. "Music" (2000)

"Music," Madonna's twelfth single to top U.S. charts, was in the running for a Grammy for Record of the Year, but lost to "Beautiful Day" by U2. The video featured Madonna (five months pregnant at the time) and comedy star Sacha Baron Cohen. "Music" has been featured in all of Madonna's shows since its release.

23. "Don't Tell Me" (2000)

When "Don't Tell Me" went gold, Madonna tied The Beatles for second place for the most gold, platinum, or multiplatinum singles -- a total of 24 -- trailing Elvis, who's way ahead of the pack with a whopping 52. "Don't Tell Me" made it to number four on U.S. charts, and the video shows Madge hanging out with cowboys and riding a mechanical bull. Yee-haw!

24. "American Life" (2003)

The first single off her highly criticized album of the same name, "American Life" lambasted the materialistic culture of America and the lack of satisfaction in the face of so much abundance. But Americans weren't ready for a political statement from the woman who used to sing about the joys of sex. This single reached the top ten (and often number-one spot) in much of Europe, as well as Canada and Japan, but only made it to number 37 on U.S. charts.

25. "Hung Up" (2006)

The first single off her album Confessions on a Dance Floor, "Hung Up" included an infectious sample from superstar dance group ABBA. A disco-fied Madonna emerged in this dance hit, signaling the return of the megastar after lukewarm album sales for American Life. "Hung Up" topped the charts in an unprecedented 41 countries, but peaked at number seven in the States.

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CONTRIBUTING WRITERS:

Helen Davies, Marjorie Dorfman, Mary Fons, Deborah Hawkins, Martin Hintz, Linnea Lundgren, David Priess, Julia Clark Robinson, Paul Seaburn, Heidi Stevens, and Steve Theunissen