12. A Wrinkle in Time by Madeleine L'Engle
The publishing house of Farrar, Straus and Giroux was smart enough to recognize the genius in L'Engle's tale for people of all ages. Published in 1962, the story was awarded the prestigious Newbery Medal the following year. Wrinkle remains one of the best-selling children's books of all time, and the story of precocious children and the magical world they discover was adapted for television in 2001. Still, L'Engle amassed 26 rejections before this success came her way.