Christopher Reeve is best remembered as Superman, both on screen and off, after portraying Clark Kent in the 1978 box-office smash Superman. After he was paralyzed during a horse-riding accident in 1995, his grace, courage, and devotion to furthering the cause of paralysis victims earned him worldwide respect and adoration. Reeve devoted the majority of his time after the accident to advocacy work, but he continued to focus on his acting career and dabbled in directing, as well. He appeared on several TV shows, including The Practice and Smallville, and directed a number of made-for-TV movies, including 1997's In the Gloaming, which was nominated for five Emmys. His final role was in Rear Window (1998), a remake of the Alfred Hitchcock classic, in which he portrayed a paralyzed architect who thinks he witnessed a murder from his apartment window. Reeve won a Screen Actors Guild Award for his performance. The courageous actor died in 2004 from cardiac arrest brought on by a reaction to antibiotics he had taken for an infection. He was 52 years old.